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Safely targeting cancer stem cells via selective catenin coactivator antagonism

Throughout our life, long-lived somatic stem cells (SSC) regenerate adult tissues both during homeostatic processes and repair after injury. The role of aberrant regulation of SSC has also recently gained prominence in the field of cancer research. Following malignant transformation, so termed cance...

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Detalles Bibliográficos
Autores principales: Lenz, Heinz-Josef, Kahn, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175086/
https://www.ncbi.nlm.nih.gov/pubmed/24975284
http://dx.doi.org/10.1111/cas.12471