Cargando…
Safely targeting cancer stem cells via selective catenin coactivator antagonism
Throughout our life, long-lived somatic stem cells (SSC) regenerate adult tissues both during homeostatic processes and repair after injury. The role of aberrant regulation of SSC has also recently gained prominence in the field of cancer research. Following malignant transformation, so termed cance...
Autores principales: | Lenz, Heinz-Josef, Kahn, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175086/ https://www.ncbi.nlm.nih.gov/pubmed/24975284 http://dx.doi.org/10.1111/cas.12471 |
Ejemplares similares
-
Nuclear receptor/Wnt beta-catenin interactions are regulated via differential CBP/p300 coactivator usage
por: Ono, Masaya, et al.
Publicado: (2018) -
The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300
por: Lukaszewicz, Agnes I., et al.
Publicado: (2019) -
Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer
por: Manegold, Philipp, et al.
Publicado: (2018) -
Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling
por: Wendt, Mathias, et al.
Publicado: (2021) -
The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
por: Kretzschmar, Kai, et al.
Publicado: (2015)