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Histone H3.3 Is Required to Maintain Replication Fork Progression after UV Damage

Unlike histone H3, which is present only in S phase, the variant histone H3.3 is expressed throughout the cell cycle [1] and is incorporated into chromatin independent of replication [2]. Recently, H3.3 has been implicated in the cellular response to ultraviolet (UV) light [3]. Here, we show that ch...

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Detalles Bibliográficos
Autores principales: Frey, Alexander, Listovsky, Tamar, Guilbaud, Guillaume, Sarkies, Peter, Sale, Julian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175177/
https://www.ncbi.nlm.nih.gov/pubmed/25201682
http://dx.doi.org/10.1016/j.cub.2014.07.077