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Conformational Analysis of the Streptococcus pneumoniae Hyaluronate Lyase and Characterization of Its Hyaluronan-specific Carbohydrate-binding Module

For a subset of pathogenic microorganisms, including Streptococcus pneumoniae, the recognition and degradation of host hyaluronan contributes to bacterial spreading through the extracellular matrix and enhancing access to host cell surfaces. The hyaluronate lyase (Hyl) presented on the surface of S....

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Detalles Bibliográficos
Autores principales: Suits, Michael D. L., Pluvinage, Benjamin, Law, Adrienne, Liu, Yan, Palma, Angelina S., Chai, Wengang, Feizi, Ten, Boraston, Alisdair B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175358/
https://www.ncbi.nlm.nih.gov/pubmed/25100731
http://dx.doi.org/10.1074/jbc.M114.578435