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Genetic and Epigenetic Changes in Chromosomally Stable and Unstable Progeny of Irradiated Cells

Radiation induced genomic instability is a well-studied phenomenon, the underlying mechanisms of which are poorly understood. Persistent oxidative stress, mitochondrial dysfunction, elevated cytokine levels and epigenetic changes are among the mechanisms invoked in the perpetuation of the phenotype....

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Detalles Bibliográficos
Autores principales: Baulch, Janet E., Aypar, Umut, Waters, Katrina M., Yang, Austin J., Morgan, William F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175465/
https://www.ncbi.nlm.nih.gov/pubmed/25251398
http://dx.doi.org/10.1371/journal.pone.0107722