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Genetic and Epigenetic Changes in Chromosomally Stable and Unstable Progeny of Irradiated Cells
Radiation induced genomic instability is a well-studied phenomenon, the underlying mechanisms of which are poorly understood. Persistent oxidative stress, mitochondrial dysfunction, elevated cytokine levels and epigenetic changes are among the mechanisms invoked in the perpetuation of the phenotype....
Autores principales: | Baulch, Janet E., Aypar, Umut, Waters, Katrina M., Yang, Austin J., Morgan, William F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175465/ https://www.ncbi.nlm.nih.gov/pubmed/25251398 http://dx.doi.org/10.1371/journal.pone.0107722 |
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