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Learning and behavioral deficits associated with the absence of the fragile X mental retardation protein: what a fly and mouse model can teach us

The Fragile X syndrome (FXS) is the most frequent form of inherited mental disability and is considered a monogenic cause of autism spectrum disorder. FXS is caused by a triplet expansion that inhibits the expression of the FMR1 gene. The gene product, the Fragile X Mental Retardation Protein (FMRP)...

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Detalles Bibliográficos
Autores principales: Santos, Ana Rita, Kanellopoulos, Alexandros K., Bagni, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175497/
https://www.ncbi.nlm.nih.gov/pubmed/25227249
http://dx.doi.org/10.1101/lm.035956.114