Robust Cre-Mediated Recombination in Small Intestinal Stem Cells Utilizing the Olfm4 Locus

The epithelium of the small intestine is the most rapidly self-renewing tissue in mammals. We previously demonstrated the existence of a long-lived pool of cycling stem cells defined by Lgr5 expression at the bottom of intestinal crypts. An Lgr5-eGFP-IRES-CreERT2 knockin allele has been instrumental...

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Detalles Bibliográficos
Autores principales: Schuijers, Jurian, van der Flier, Laurens G., van Es, Johan, Clevers, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175542/
https://www.ncbi.nlm.nih.gov/pubmed/25254337
http://dx.doi.org/10.1016/j.stemcr.2014.05.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175542/
https://www.ncbi.nlm.nih.gov/pubmed/25254337
http://dx.doi.org/10.1016/j.stemcr.2014.05.018

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