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Genetic Activation of Hedgehog Signaling Unbalances the Rate of Neural Stem Cell Renewal by Increasing Symmetric Divisions

In the adult brain, self-renewal is essential for the persistence of neural stem cells (NSCs) throughout life, but its regulation is still poorly understood. One NSC can give birth to two NSCs or one NSC and one transient progenitor. A correct balance is necessary for the maintenance of germinal are...

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Detalles Bibliográficos
Autores principales: Ferent, Julien, Cochard, Loïc, Faure, Hélène, Taddei, Maurizio, Hahn, Heidi, Ruat, Martial, Traiffort, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175546/
https://www.ncbi.nlm.nih.gov/pubmed/25254344
http://dx.doi.org/10.1016/j.stemcr.2014.05.016