Unexpected structure for the N-terminal domain of hepatitis C virus envelope glycoprotein E1

Hepatitis C virus (HCV) infection remains a major health problem worldwide. HCV entry into host cells and membrane fusion are achieved by two envelope glycoproteins, E1 and E2. We report here the 3.5-Å resolution crystal structure of the N-terminal domain of the HCV E1 ectodomain, which reveals a co...

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Detalles Bibliográficos
Autores principales: El Omari, Kamel, Iourin, Oleg, Kadlec, Jan, Sutton, Geoff, Harlos, Karl, Grimes, Jonathan M., Stuart, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175578/
https://www.ncbi.nlm.nih.gov/pubmed/25224686
http://dx.doi.org/10.1038/ncomms5874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175578/
https://www.ncbi.nlm.nih.gov/pubmed/25224686
http://dx.doi.org/10.1038/ncomms5874

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