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Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma

BACKGROUND: Despite modern advances in treatment, skin cancer is still one of the most common causes of death in the western countries. Chemotherapy plays an important role in melanoma management. Tamoxifen has been used either alone or in- combination with other chemotherapeutic agents to treat mel...

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Detalles Bibliográficos
Autores principales: Mohammad, Naoshad, Malvi, Parmanand, Meena, Avtar Singh, Singh, Shivendra Vikram, Chaube, Balkrishna, Vannuruswamy, Garikapati, Kulkarni, Mahesh J, Bhat, Manoj Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175626/
https://www.ncbi.nlm.nih.gov/pubmed/25178635
http://dx.doi.org/10.1186/1476-4598-13-204