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RETRACTED ARTICLE: A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China

BACKGROUND: GP78 is a membrane-anchored ubiquitin ligase mediating the degradation of 3-hydroxy-3-methyl-glutaryl-CoA coenzyme A reductase (HMGCR) and Insig-1, which was very essential for the synthesis of cholesterol process. Cholesterol levels have a causal role in the development of cardiovascula...

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Detalles Bibliográficos
Autores principales: Cha, Erdenbat, Fu, Zhen-Yan, Ma, Yi-Tong, Zhu, Qing, Xie, Xiang, Liu, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175632/
https://www.ncbi.nlm.nih.gov/pubmed/25200441
http://dx.doi.org/10.1186/1476-511X-13-147