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RETRACTED ARTICLE: A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China
BACKGROUND: GP78 is a membrane-anchored ubiquitin ligase mediating the degradation of 3-hydroxy-3-methyl-glutaryl-CoA coenzyme A reductase (HMGCR) and Insig-1, which was very essential for the synthesis of cholesterol process. Cholesterol levels have a causal role in the development of cardiovascula...
Autores principales: | Cha, Erdenbat, Fu, Zhen-Yan, Ma, Yi-Tong, Zhu, Qing, Xie, Xiang, Liu, Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175632/ https://www.ncbi.nlm.nih.gov/pubmed/25200441 http://dx.doi.org/10.1186/1476-511X-13-147 |
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