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Co-detection and sequencing of genes and transcripts from the same single cells facilitated by a microfluidics platform

Despite the recent advance of single-cell gene expression analyses, co-measurement of both genomic and transcriptional signatures at the single-cell level has not been realized. However such analysis is necessary in order to accurately delineate how genetic information is transcribed, expressed, and...

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Detalles Bibliográficos
Autores principales: Han, Lin, Zi, Xiaoyuan, Garmire, Lana X., Wu, Yu, Weissman, Sherman M., Pan, Xinghua, Fan, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175731/
https://www.ncbi.nlm.nih.gov/pubmed/25255798
http://dx.doi.org/10.1038/srep06485