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A molecular mechanism of mitotic centrosome assembly in Drosophila

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both...

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Detalles Bibliográficos
Autores principales: Conduit, Paul T, Richens, Jennifer H, Wainman, Alan, Holder, James, Vicente, Catarina C, Pratt, Metta B, Dix, Carly I, Novak, Zsofia A, Dobbie, Ian M, Schermelleh, Lothar, Raff, Jordan W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175739/
https://www.ncbi.nlm.nih.gov/pubmed/25149451
http://dx.doi.org/10.7554/eLife.03399