αMSH Blunts Endotoxin-Induced MuRF1 and Atrogin-1 Upregulation in Skeletal Muscle by Modulating NF-κB and Akt/FoxO1 Pathway

Alpha melanocyte stimulating hormone (αMSH) has been shown to have anti-inflammatory and anticachectic actions. We hypothesized that αMSH administration could attenuate the effect of lipopolysaccharide (LPS) on the skeletal muscle through modifications in IGF-Akt-FoxO1 pathway, or/and in serum corti...

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Detalles Bibliográficos
Autores principales: Martín, Ana Isabel, Gómez-SanMiguel, Ana Belén, Gómez-Moreira, Carolina, Villanúa, María Ángeles, López-Calderón, Asunción
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175750/
https://www.ncbi.nlm.nih.gov/pubmed/25294954
http://dx.doi.org/10.1155/2014/179368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175750/
https://www.ncbi.nlm.nih.gov/pubmed/25294954
http://dx.doi.org/10.1155/2014/179368

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