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αMSH Blunts Endotoxin-Induced MuRF1 and Atrogin-1 Upregulation in Skeletal Muscle by Modulating NF-κB and Akt/FoxO1 Pathway
Alpha melanocyte stimulating hormone (αMSH) has been shown to have anti-inflammatory and anticachectic actions. We hypothesized that αMSH administration could attenuate the effect of lipopolysaccharide (LPS) on the skeletal muscle through modifications in IGF-Akt-FoxO1 pathway, or/and in serum corti...
Autores principales: | Martín, Ana Isabel, Gómez-SanMiguel, Ana Belén, Gómez-Moreira, Carolina, Villanúa, María Ángeles, López-Calderón, Asunción |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175750/ https://www.ncbi.nlm.nih.gov/pubmed/25294954 http://dx.doi.org/10.1155/2014/179368 |
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