Talpid3-Binding Centrosomal Protein Cep120 Is Required for Centriole Duplication and Proliferation of Cerebellar Granule Neuron Progenitors

Granule neuron progenitors (GNPs) are the most abundant neuronal type in the cerebellum. GNP proliferation and thus cerebellar development require Sonic hedgehog (Shh) secreted from Purkinje cells. Shh signaling occurs in primary cilia originating from the mother centriole. Centrioles replicate only...

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Detalles Bibliográficos
Autores principales: Wu, Chuanqing, Yang, Mei, Li, Juan, Wang, Chengbing, Cao, Ting, Tao, Kaixiong, Wang, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176001/
https://www.ncbi.nlm.nih.gov/pubmed/25251415
http://dx.doi.org/10.1371/journal.pone.0107943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176001/
https://www.ncbi.nlm.nih.gov/pubmed/25251415
http://dx.doi.org/10.1371/journal.pone.0107943

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