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Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis
BACKGROUND: Basal-like breast cancer is a heterogeneous disease characterized by the expression of basal cell markers, no estrogen or progesterone receptor expression and a lack of HER2 ov erexpression. Recent studies have linked activation of the Wnt/β-catenin pathway, and its downstream target, My...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176121/ https://www.ncbi.nlm.nih.gov/pubmed/24171719 http://dx.doi.org/10.1186/1476-4598-12-132 |