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6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α

BACKGROUND: 6-Shogaol is a promising antitumor agent isolated from dietary ginger (Zingiber officinale). However, little is known about the efficacy of 6-shogaol on leukemia cells. Here we investigated the underlying mechanism of 6-shogaol induced apoptosis in human leukemia cells in vitro and in vi...

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Detalles Bibliográficos
Autores principales: Liu, Qun, Peng, Yong-Bo, Zhou, Ping, Qi, Lian-Wen, Zhang, Mu, Gao, Ning, Liu, E-Hu, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176122/
https://www.ncbi.nlm.nih.gov/pubmed/24215632
http://dx.doi.org/10.1186/1476-4598-12-135