Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prolactin pathway

BACKGROUND: Tumors may develop resistance to specific angiogenic inhibitors via activation of alternative pathways. Therefore, multiple angiogenic pathways should be targeted to achieve significant angiogenic blockade. In this study we investigated the effects of a combined application of the angiog...

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Detalles Bibliográficos
Autores principales: Oliveira-Ferrer, Leticia, Wellbrock, Jasmin, Bartsch, Udo, Murga Penas, Eva Maria, Hauschild, Jessica, Klokow, Marianne, Bokemeyer, Carsten, Fiedler, Walter, Schuch, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176123/
https://www.ncbi.nlm.nih.gov/pubmed/24257371
http://dx.doi.org/10.1186/1476-4598-12-144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176123/
https://www.ncbi.nlm.nih.gov/pubmed/24257371
http://dx.doi.org/10.1186/1476-4598-12-144

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