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Human herpesviruses-encoded dUTPases: a family of proteins that modulate dendritic cell function and innate immunity

We have previously shown that Epstein-Barr virus (EBV)-encoded dUTPase can modulate innate immune responses through the activation of TLR2 and NF-κB signaling. However, whether this novel immune function of the dUTPase is specific for EBV or a common property of the Herpesviridae family is not known...

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Detalles Bibliográficos
Autores principales: Ariza, Maria Eugenia, Glaser, Ronald, Williams, Marshall V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176148/
https://www.ncbi.nlm.nih.gov/pubmed/25309527
http://dx.doi.org/10.3389/fmicb.2014.00504