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3′LIFE: a functional assay to detect miRNA targets in high-throughput

MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene output at the post-transcriptional level by targeting degenerate elements primarily in 3′untranslated regions (3′UTRs) of mRNAs. Individual miRNAs can regulate networks of hundreds of genes, yet for the majority of miRNAs few, if any, t...

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Detalles Bibliográficos
Autores principales: Wolter, Justin M., Kotagama, Kasuen, Pierre-Bez, Alexandra C., Firago, Mari, Mangone, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176154/
https://www.ncbi.nlm.nih.gov/pubmed/25074381
http://dx.doi.org/10.1093/nar/gku626