Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light

Short-wave ultraviolet light induces both mildly helix-distorting cyclobutane pyrimidine dimers (CPDs) and severely distorting (6–4) pyrimidine pyrimidone photoproducts ((6–4)PPs). The only DNA polymerase (Pol) that is known to replicate efficiently across CPDs is Polη, a member of the Y family of t...

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Detalles Bibliográficos
Autores principales: Jansen, Jacob G., Temviriyanukul, Piya, Wit, Niek, Delbos, Frédéric, Reynaud, Claude-Agnès, Jacobs, Heinz, de Wind, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176164/
https://www.ncbi.nlm.nih.gov/pubmed/25170086
http://dx.doi.org/10.1093/nar/gku779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176164/
https://www.ncbi.nlm.nih.gov/pubmed/25170086
http://dx.doi.org/10.1093/nar/gku779

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