Cargando…
Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light
Short-wave ultraviolet light induces both mildly helix-distorting cyclobutane pyrimidine dimers (CPDs) and severely distorting (6–4) pyrimidine pyrimidone photoproducts ((6–4)PPs). The only DNA polymerase (Pol) that is known to replicate efficiently across CPDs is Polη, a member of the Y family of t...
Autores principales: | Jansen, Jacob G., Temviriyanukul, Piya, Wit, Niek, Delbos, Frédéric, Reynaud, Claude-Agnès, Jacobs, Heinz, de Wind, Niels |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176164/ https://www.ncbi.nlm.nih.gov/pubmed/25170086 http://dx.doi.org/10.1093/nar/gku779 |
Ejemplares similares
-
Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage
por: Wit, Niek, et al.
Publicado: (2015) -
DNA polymerase zeta is required for proliferation of normal mammalian cells
por: Lange, Sabine S., et al.
Publicado: (2012) -
FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress
por: Yang, Yeran, et al.
Publicado: (2015) -
Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells
por: Lerner, Leticia K., et al.
Publicado: (2017) -
Ultraviolet-induced RNA:DNA hybrids interfere with chromosomal DNA synthesis
por: Kouzminova, Elena A, et al.
Publicado: (2021)