Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines

BACKGROUND: Lysine-specific demethylase 1 (LSD1, also known as KDM1A and AOF2) is a chromatin-modifying activity that catalyzes the removal of methyl groups from lysine residues in histone and non-histone proteins, regulating gene transcription. LSD1 is overexpressed in several cancer types, and che...

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Detalles Bibliográficos
Autores principales: Konovalov, Sergiy, Garcia-Bassets, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176291/
https://www.ncbi.nlm.nih.gov/pubmed/24165091
http://dx.doi.org/10.1186/1757-2215-6-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176291/
https://www.ncbi.nlm.nih.gov/pubmed/24165091
http://dx.doi.org/10.1186/1757-2215-6-75

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