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Phosphorylated fragile X mental retardation protein at serine 499, is reduced in cerebellar vermis and superior frontal cortex of subjects with autism: implications for fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling

Lohith et al. (Mol Autism 4:15, 2013) recently identified increased metabotropic glutamate receptor 5 (mGluR5) expression in the frontal cortex (FC) of subjects with fragile X syndrome. These results are consistent with postmortem findings in cerebellar vermis and FC of subjects with autism (Fatemi...

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Detalles Bibliográficos
Autores principales: Rustan, Øyvind G, Folsom, Timothy D, Yousefi, Mahtab K, Fatemi, S Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176299/
https://www.ncbi.nlm.nih.gov/pubmed/24180586
http://dx.doi.org/10.1186/2040-2392-4-41