Rolling circle replication requires single-stranded DNA binding protein to avoid termination and production of double-stranded DNA

In rolling circle replication, a circular template of DNA is replicated as a long single-stranded DNA concatamer that spools off when a strand displacing polymerase traverses the circular template. The current view is that this type of replication can only produce single-stranded DNA, because the on...

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Detalles Bibliográficos
Autores principales: Ducani, Cosimo, Bernardinelli, Giulio, Högberg, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176320/
https://www.ncbi.nlm.nih.gov/pubmed/25120268
http://dx.doi.org/10.1093/nar/gku737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176320/
https://www.ncbi.nlm.nih.gov/pubmed/25120268
http://dx.doi.org/10.1093/nar/gku737

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