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Rolling circle replication requires single-stranded DNA binding protein to avoid termination and production of double-stranded DNA
In rolling circle replication, a circular template of DNA is replicated as a long single-stranded DNA concatamer that spools off when a strand displacing polymerase traverses the circular template. The current view is that this type of replication can only produce single-stranded DNA, because the on...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176320/ https://www.ncbi.nlm.nih.gov/pubmed/25120268 http://dx.doi.org/10.1093/nar/gku737 |