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Genomic HEXploring allows landscaping of novel potential splicing regulatory elements

Effective splice site selection is critically controlled by flanking splicing regulatory elements (SREs) that can enhance or repress splice site use. Although several computational algorithms currently identify a multitude of potential SRE motifs, their predictive power with respect to mutation effe...

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Detalles Bibliográficos
Autores principales: Erkelenz, Steffen, Theiss, Stephan, Otte, Marianne, Widera, Marek, Peter, Jan Otto, Schaal, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176321/
https://www.ncbi.nlm.nih.gov/pubmed/25147205
http://dx.doi.org/10.1093/nar/gku736