Cargando…

Genomic HEXploring allows landscaping of novel potential splicing regulatory elements

Effective splice site selection is critically controlled by flanking splicing regulatory elements (SREs) that can enhance or repress splice site use. Although several computational algorithms currently identify a multitude of potential SRE motifs, their predictive power with respect to mutation effe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Erkelenz, Steffen, Theiss, Stephan, Otte, Marianne, Widera, Marek, Peter, Jan Otto, Schaal, Heiner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176321/ https://www.ncbi.nlm.nih.gov/pubmed/25147205 http://dx.doi.org/10.1093/nar/gku736

Ejemplares similares

HEXploring of the HIV-1 genome allows landscaping of new potential splicing regulatory elements
por: Erkelenz, Steffen, et al.
Publicado: (2013)

Modeling splicing outcome by combining 5′ss strength and splicing regulatory elements
por: Müller, Lisa, et al.
Publicado: (2022)

Succession of splicing regulatory elements determines cryptic 5΄ss functionality
por: Brillen, Anna-Lena, et al.
Publicado: (2017)

Balanced splicing at the Tat-specific HIV-1 3′ss A3 is critical for HIV-1 replication
por: Erkelenz, Steffen, et al.
Publicado: (2015)

Frequent Gain and Loss of Intronic Splicing Regulatory Elements during the Evolution of Vertebrates
por: Voelker, Rodger B., et al.
Publicado: (2012)

Functional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12
por: Haque, Ariful, et al.
Publicado: (2010)

Ranking noncanonical 5′ splice site usage by genome-wide RNA-seq analysis and splicing reporter assays
por: Erkelenz, Steffen, et al.
Publicado: (2018)

Overlapping splicing regulatory motifs—combinatorial effects on splicing
por: Goren, Amir, et al.
Publicado: (2010)

A purine-rich element in foamy virus pol regulates env splicing and gag/pol expression
por: Moschall, Rebecca, et al.
Publicado: (2017)

An Ultraconserved Element (UCE) controls homeostatic splicing of ARGLU1 mRNA
por: Pirnie, Stephan P., et al.
Publicado: (2017)

Mutually exclusive splicing regulates the Na(v) 1.6 sodium channel function through a combinatorial mechanism that involves three distinct splicing regulatory elements and their ligands
por: Zubović, Lorena, et al.
Publicado: (2012)

Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors
por: Culler, Stephanie J., et al.
Publicado: (2010)

A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction
por: Widera, Marek, et al.
Publicado: (2014)

A G-tract element in apoptotic agents-induced alternative splicing
por: Hai, Yan, et al.
Publicado: (2008)

Splicing of internal large exons is defined by novel cis-acting sequence elements
por: Bolisetty, Mohan T., et al.
Publicado: (2012)

The hepatitis B virus PRE contains a splicing regulatory element
por: Heise, Tilman, et al.
Publicado: (2006)

An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis
por: Schmitz, Katharina, et al.
Publicado: (2021)

Regulatory mechanisms for 3′-end alternative splicing and polyadenylation of the Glial Fibrillary Acidic Protein, GFAP, transcript
por: Blechingberg, Jenny, et al.
Publicado: (2007)

HnRNP A1 controls a splicing regulatory circuit promoting mesenchymal-to-epithelial transition
por: Bonomi, Serena, et al.
Publicado: (2013)

A competitive regulatory mechanism discriminates between juxtaposed splice sites and pri-miRNA structures
por: Mattioli, Chiara, et al.
Publicado: (2013)

Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication
por: Shkreta, Lulzim, et al.
Publicado: (2017)

Gymnotic Delivery of LNA Mixmers Targeting Viral SREs Induces HIV-1 mRNA Degradation
por: Hillebrand, Frank, et al.
Publicado: (2019)

A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells
por: Ajiro, Masahiko, et al.
Publicado: (2016)

Translational control of the interferon regulatory factor 2 mRNA by IRES element
por: Dhar, Debojyoti, et al.
Publicado: (2007)

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts
por: Sorber, Katherine, et al.
Publicado: (2011)

RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events
por: Buratti, Emanuele, et al.
Publicado: (2007)

SOX9 has distinct regulatory roles in alternative splicing and transcription
por: Girardot, Michael, et al.
Publicado: (2018)

Limited complementarity between U1 snRNA and a retroviral 5′ splice site permits its attenuation via RNA secondary structure
por: Zychlinski, Daniela, et al.
Publicado: (2009)

Co-regulation of alternative splicing by diverse splicing factors in Caenorhabditis elegans
por: Barberan-Soler, Sergio, et al.
Publicado: (2011)

Splicing proofreading at 5′ splice sites by ATPase Prp28p
por: Yang, Fei, et al.
Publicado: (2013)

Rbm20 regulates titin alternative splicing as a splicing repressor
por: Li, Shijun, et al.
Publicado: (2013)

Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation
por: Thomas, Christie P., et al.
Publicado: (2010)

Alternative splicing at GYNNGY 5′ splice sites: more noise, less regulation
por: Wang, Meng, et al.
Publicado: (2014)

U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing
por: Fukumura, Kazuhiro, et al.
Publicado: (2009)

Alternative splicing of CD200 is regulated by an exonic splicing enhancer and SF2/ASF
por: Chen, Zhiqi, et al.
Publicado: (2010)

Extended base pair complementarity between U1 snRNA and the 5′ splice site does not inhibit splicing in higher eukaryotes, but rather increases 5′ splice site recognition
por: Freund, Marcel, et al.
Publicado: (2005)

RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP
por: Muniz, Lisa, et al.
Publicado: (2013)

The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA splicing
por: Sciabica, Kathryn S., et al.
Publicado: (2006)

An Alu-derived intronic splicing enhancer facilitates intronic processing and modulates aberrant splicing in ATM
por: Pastor, Tibor, et al.
Publicado: (2009)

Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage
por: Comiskey, Daniel F., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7vdvn2vog5od6f6tfedcq57as2