DEAD-box RNA helicase domains exhibit a continuum between complete functional independence and high thermodynamic coupling in nucleotide and RNA duplex recognition

DEAD-box helicases catalyze the non-processive unwinding of double-stranded RNA (dsRNA) at the expense of adenosine triphosphate (ATP) hydrolysis. Nucleotide and RNA binding and unwinding are mediated by the RecA domains of the helicase core, but their cooperation in these processes remains poorly u...

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Detalles Bibliográficos
Autores principales: Samatanga, Brighton, Klostermeier, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176333/
https://www.ncbi.nlm.nih.gov/pubmed/25123660
http://dx.doi.org/10.1093/nar/gku747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176333/
https://www.ncbi.nlm.nih.gov/pubmed/25123660
http://dx.doi.org/10.1093/nar/gku747

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