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Mycobacterium RbpA cooperates with the stress-response σ(B) subunit of RNA polymerase in promoter DNA unwinding

RbpA, a transcriptional activator that is essential for Mycobacterium tuberculosis replication and survival during antibiotic treatment, binds to RNA polymerase (RNAP) in the absence of promoter DNA. It has been hypothesized that RbpA stimulates housekeeping gene expression by promoting assembly of...

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Detalles Bibliográficos
Autores principales: Hu, Yangbo, Morichaud, Zakia, Sudalaiyadum Perumal, Ayyappasamy, Roquet-Baneres, Françoise, Brodolin, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176334/
https://www.ncbi.nlm.nih.gov/pubmed/25122744
http://dx.doi.org/10.1093/nar/gku742