MRTF-A steers an epigenetic complex to activate endothelin-induced pro-inflammatory transcription in vascular smooth muscle cells

Endothelin (ET-1) was initially identified as a potent vasoconstrictor contributing to the maintenance of vascular rhythm. Later studies have implicated ET-1, when aberrantly up-regulated within the vasculature, in a range of human pathologies associated with disruption of vascular homeostasis. ET-1...

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Detalles Bibliográficos
Autores principales: Yang, Yuyu, Cheng, Xian, Tian, Wenfang, Zhou, Bisheng, Wu, Xiaoyan, Xu, Huihui, Fang, Fei, Fang, Mingming, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176337/
https://www.ncbi.nlm.nih.gov/pubmed/25159611
http://dx.doi.org/10.1093/nar/gku776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176337/
https://www.ncbi.nlm.nih.gov/pubmed/25159611
http://dx.doi.org/10.1093/nar/gku776

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