Multivariate inference of pathway activity in host immunity and response to therapeutics

Developing a quantitative view of how biological pathways are regulated in response to environmental factors is central for understanding of disease phenotypes. We present a computational framework, named Multivariate Inference of Pathway Activity (MIPA), which quantifies degree of activity induced...

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Detalles Bibliográficos
Autores principales: Goel, Gautam, Conway, Kara L., Jaeger, Martin, Netea, Mihai G., Xavier, Ramnik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176341/
https://www.ncbi.nlm.nih.gov/pubmed/25147207
http://dx.doi.org/10.1093/nar/gku722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176341/
https://www.ncbi.nlm.nih.gov/pubmed/25147207
http://dx.doi.org/10.1093/nar/gku722

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