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Multivariate inference of pathway activity in host immunity and response to therapeutics
Developing a quantitative view of how biological pathways are regulated in response to environmental factors is central for understanding of disease phenotypes. We present a computational framework, named Multivariate Inference of Pathway Activity (MIPA), which quantifies degree of activity induced...
Autores principales: | Goel, Gautam, Conway, Kara L., Jaeger, Martin, Netea, Mihai G., Xavier, Ramnik J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176341/ https://www.ncbi.nlm.nih.gov/pubmed/25147207 http://dx.doi.org/10.1093/nar/gku722 |
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