Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation

Artificial transcription factors (ATFs) and genomic nucleases based on a DNA binding platform consisting of multiple zinc finger domains are currently being developed for clinical applications. However, no genome-wide investigations into their binding specificity have been performed. We have created...

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Detalles Bibliográficos
Autores principales: Grimmer, Matthew R., Stolzenburg, Sabine, Ford, Ethan, Lister, Ryan, Blancafort, Pilar, Farnham, Peggy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176344/
https://www.ncbi.nlm.nih.gov/pubmed/25122745
http://dx.doi.org/10.1093/nar/gku708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176344/
https://www.ncbi.nlm.nih.gov/pubmed/25122745
http://dx.doi.org/10.1093/nar/gku708

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