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Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation
Artificial transcription factors (ATFs) and genomic nucleases based on a DNA binding platform consisting of multiple zinc finger domains are currently being developed for clinical applications. However, no genome-wide investigations into their binding specificity have been performed. We have created...
Autores principales: | Grimmer, Matthew R., Stolzenburg, Sabine, Ford, Ethan, Lister, Ryan, Blancafort, Pilar, Farnham, Peggy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176344/ https://www.ncbi.nlm.nih.gov/pubmed/25122745 http://dx.doi.org/10.1093/nar/gku708 |
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