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40S recruitment in the absence of eIF4G/4A by EMCV IRES refines the model for translation initiation on the archetype of Type II IRESs

Initiation of translation on Type II IRESs, such as those of EMCV and FMDV viruses, has been well documented in the recent years. For EMCV, the current model argues for a mechanism in which the key interaction necessary for the pre-initiation complex recruitment is eIF4G binding to the central J-K d...

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Detalles Bibliográficos
Autores principales: Chamond, Nathalie, Deforges, Jules, Ulryck, Nathalie, Sargueil, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176346/
https://www.ncbi.nlm.nih.gov/pubmed/25159618
http://dx.doi.org/10.1093/nar/gku720