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Initiator protein dimerization plays a key role in replication control of Vibrio cholerae chromosome 2

RctB, the initiator of replication of Vibrio cholerae chromosome 2 (chr2), binds to the origin of replication to specific 12-mer sites both as a monomer and a dimer. Binding to 12-mers is essential for initiation. The monomers also bind to a second kind of site, 39-mers, which inhibits initiation. M...

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Detalles Bibliográficos
Autores principales: Jha, Jyoti K., Ghirlando, Rodolfo, Chattoraj, Dhruba K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176361/
https://www.ncbi.nlm.nih.gov/pubmed/25159619
http://dx.doi.org/10.1093/nar/gku771