Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion

The bacterial transcription factor LacI loops DNA by binding to two separate locations on the DNA simultaneously. Despite being one of the best-studied model systems for transcriptional regulation, the number and conformations of loop structures accessible to LacI remain unclear, though the importan...

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Detalles Bibliográficos
Autores principales: Johnson, Stephanie, van de Meent, Jan-Willem, Phillips, Rob, Wiggins, Chris H., Lindén, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176382/
https://www.ncbi.nlm.nih.gov/pubmed/25120267
http://dx.doi.org/10.1093/nar/gku563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176382/
https://www.ncbi.nlm.nih.gov/pubmed/25120267
http://dx.doi.org/10.1093/nar/gku563

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