Influence of d-glutamine and d-glutamic acid sequences in optical peptide probes targeted against the cholecystokinin-2/gastrin-receptor on binding affinity, specificity and pharmacokinetic properties

BACKGROUND: Image-based diagnosis of tumours can be advanced and improved by targeted strategies addressing malignant molecular structures. A promising molecular target is the cholecystokinin-2-receptor (CCK2R) which can be targeted by high-affinity peptides called minigastrins. Here we present how...

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Detalles Bibliográficos
Autores principales: Kossatz, Susanne, Mansi, Rosalba, Béhé, Martin, Czerney, Peter, Hilger, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176481/
https://www.ncbi.nlm.nih.gov/pubmed/24238262
http://dx.doi.org/10.1186/2191-219X-3-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176481/
https://www.ncbi.nlm.nih.gov/pubmed/24238262
http://dx.doi.org/10.1186/2191-219X-3-75

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