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Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

Multiple sclerosis (MS) is a chronic demyelinating disease of unknown etiology that affects the CNS. While current therapies are primarily directed against the immune system, the new challenge is to address progressive MS with remyelinating and neuroprotective strategies. Here, we develop a highly r...

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Detalles Bibliográficos
Autores principales: Douvaras, Panagiotis, Wang, Jing, Zimmer, Matthew, Hanchuk, Stephanie, O’Bara, Melanie A., Sadiq, Saud, Sim, Fraser J., Goldman, James, Fossati, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176529/
https://www.ncbi.nlm.nih.gov/pubmed/25254339
http://dx.doi.org/10.1016/j.stemcr.2014.06.012