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Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells
Multiple sclerosis (MS) is a chronic demyelinating disease of unknown etiology that affects the CNS. While current therapies are primarily directed against the immune system, the new challenge is to address progressive MS with remyelinating and neuroprotective strategies. Here, we develop a highly r...
Autores principales: | Douvaras, Panagiotis, Wang, Jing, Zimmer, Matthew, Hanchuk, Stephanie, O’Bara, Melanie A., Sadiq, Saud, Sim, Fraser J., Goldman, James, Fossati, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176529/ https://www.ncbi.nlm.nih.gov/pubmed/25254339 http://dx.doi.org/10.1016/j.stemcr.2014.06.012 |
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