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Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1
Direct conversion of nonneural cells to functional neurons holds great promise for neurological disease modeling and regenerative medicine. We previously reported rapid reprogramming of mouse embryonic fibroblasts (MEFs) into mature induced neuronal (iN) cells by forced expression of three transcrip...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176533/ https://www.ncbi.nlm.nih.gov/pubmed/25254342 http://dx.doi.org/10.1016/j.stemcr.2014.05.020 |