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Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1

Direct conversion of nonneural cells to functional neurons holds great promise for neurological disease modeling and regenerative medicine. We previously reported rapid reprogramming of mouse embryonic fibroblasts (MEFs) into mature induced neuronal (iN) cells by forced expression of three transcrip...

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Detalles Bibliográficos
Autores principales: Chanda, Soham, Ang, Cheen Euong, Davila, Jonathan, Pak, ChangHui, Mall, Moritz, Lee, Qian Yi, Ahlenius, Henrik, Jung, Seung Woo, Südhof, Thomas C., Wernig, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176533/
https://www.ncbi.nlm.nih.gov/pubmed/25254342
http://dx.doi.org/10.1016/j.stemcr.2014.05.020