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Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice

BACKGROUND: Glial cell activation and overproduction of inflammatory mediators in the central nervous system (CNS) have been implicated in acute traumatic injuries to the CNS, including spinal cord injury (SCI). Elevated levels of the proinflammatory cytokine tumor necrosis factor (TNF), which exist...

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Detalles Bibliográficos
Autores principales: Novrup, Hans G, Bracchi-Ricard, Valerie, Ellman, Ditte G, Ricard, Jerome, Jain, Anjana, Runko, Erik, Lyck, Lise, Yli-Karjanmaa, Minna, Szymkowski, David E, Pearse, Damien D, Lambertsen, Kate L, Bethea, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176557/
https://www.ncbi.nlm.nih.gov/pubmed/25204558
http://dx.doi.org/10.1186/s12974-014-0159-6