KML001, a Telomere-Targeting Drug, Sensitizes Glioblastoma Cells to Temozolomide Chemotherapy and Radiotherapy through DNA Damage and Apoptosis

Standard treatment for glioblastoma comprises surgical resection, chemotherapy with temozolomide, and radiotherapy. Nevertheless, majority of glioblastoma patients have recurrence from resistance to the cytotoxic conventional therapies. We examined combinational effects of KML001, an arsenic compoun...

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Detalles Bibliográficos
Autores principales: Woo, Seon Rang, Ham, Yunhee, Kang, Wonyoung, Yang, Heekyoung, Kim, Sujong, Jin, Juyoun, Joo, Kyeung Min, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176651/
https://www.ncbi.nlm.nih.gov/pubmed/25295271
http://dx.doi.org/10.1155/2014/747415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176651/
https://www.ncbi.nlm.nih.gov/pubmed/25295271
http://dx.doi.org/10.1155/2014/747415

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