Cargando…

CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells

BACKGROUND: Chronic myeloid leukemia is a clonal myeloproliferative disorder disease in which BCR/ABL plays an important role as an oncoprotein and molecular target. Despite the success of targeted therapy using tyrosine kinase inhibitors, CML remains largely incurable, most likely due to the treatm...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Guoqiang, Zhang, Hongju, Wang, Jian, Zhang, Yujuan, Xu, Hua, Wang, Chijuan, Zhang, Hairui, Ma, Li, Li, Qinghua, Pang, Tianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176735/
https://www.ncbi.nlm.nih.gov/pubmed/24257075
http://dx.doi.org/10.1186/1475-2867-13-117