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Differential triggering of spontaneous glutamate release by P/Q-, N-, and R-type Ca(2+) channels
The role of voltage-gated Ca(2+) channels (VGCCs) in spontaneous miniature neurotransmitter release is incompletely understood. Here we show that stochastic opening of P/Q-, N-, and R-type VGCCs accounts for ~50% of all spontaneous glutamate release at rat cultured hippocampal synapses, and that R-t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176737/ https://www.ncbi.nlm.nih.gov/pubmed/24185424 http://dx.doi.org/10.1038/nn.3563 |