Differential triggering of spontaneous glutamate release by P/Q-, N-, and R-type Ca(2+) channels

The role of voltage-gated Ca(2+) channels (VGCCs) in spontaneous miniature neurotransmitter release is incompletely understood. Here we show that stochastic opening of P/Q-, N-, and R-type VGCCs accounts for ~50% of all spontaneous glutamate release at rat cultured hippocampal synapses, and that R-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ermolyuk, Yaroslav S., Alder, Felicity G., Surges, Rainer, Pavlov, Ivan Y., Timofeeva, Yulia, Kullmann, Dimitri M., Volynski, Kirill E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176737/
https://www.ncbi.nlm.nih.gov/pubmed/24185424
http://dx.doi.org/10.1038/nn.3563

Ejemplares similares

Ejemplares similares